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Recent Research Projects An overlapping clustering method for protein interaction data (more...) Computational selection of transcriptomics experiments (more...) Analysis of the evolution of MAPK networks in plants (more...) Automatic annotation of gene families (more...) Semantic similarity measures (more...) Spectral methods for clustering protein sequences (more...) Techniques for integrating different protein-protein interaction experiments (more...) Methods for denoising large scale protein-protein interaction experiments (more...) Protein-protein interaction prediction (more...) Prediction of gene essentiality from genomic features (more...) Prediction of protein function in E. Coli (more...) Quantifying environmental adaptation of metabolic pathways in metagenomics (more...)
A
census of human soluble protein complexes Cell,
2012 Aug 31;150(5):1068-81.
GFam:
a platform for automatic annotation of gene
families Nucleic
Acids Res. 2012 Jul 11.Detecting
overlapping protein complexes in
protein-protein interaction networks Nature Methods,
2012 Mar 18;9(5):471-2. doi:
10.1038/nmeth.1938.
Improving
GO semantic similarity measures by exploring
the ontology beneath the terms and modelling
uncertainty Bioinformatics, 2012,
28, pp. 1383Quantifying environmental adaptation of metabolic pathways in metagenomics, Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1374-9 Statistical analysis of the genomic distribution and correlation of regulatory elements in the ENCODE regions, Genome Research, 2007,17(6):787-97 Global landscape of protein complexes in the yeast Saccharomyces cerevisiae, Nature, 2006, Mar 30,440(7084):637-43 Spectral Clustering of Proteins Sequences, Nucleic Acids Research 2006, Mar 17;34(5):1571-80 Predicting Essential Genes in Fungal Genomes, Genome Research, 2006, 16 (9): 1126-35 Predicting interactions in protein networks by completing defective cliques, Bioinformatics 2006, Apr 1;22(7):823-9 Integration of curated databases to identify genotype-phenotype associations, BMC Genomics. 2006, Oct 12;7:257 Assessing the Limits of Genomic Data Integration for Protein-Protein Interactions, Genome Research, Jul 2005, 15: 945 – 953 Current Lab Funding - A GPU-based high performance system for discovering consensus domain architecture and functional annotation of protein families BBSRC, £ 114,000 started in September 2009 - Overlapping community detection methods for biological applications Newton International Fellowship, £ 98,000 started in February 2009 - Development of graph theoretic approaches to predict protein function by integrating large scale heterogeneous data BBSRC New Investigator Grant, £ 517,000 started in October 2008 - BioSynLab: a software platform for the analysis of metabolic data Park (Partnership in Accessible Research and Knowledge), £ 53,202 started in October 2007 - A pilot study of graph theoretic approaches for predicting protein-protein interactions Royal Holloway Research Strategy Fund, £5350 |
| Contact
information Dr Alberto Paccanaro
Department of Computer Science Royal Holloway, University of London Egham, TW20 0EX UK Phone: +44 1784 414239 Fax: +44 1784 439786 Email: alberto - at - cs.rhul.ac.uk (replace -at- with @ ) |