SIMPLE SEQUENCES IN GENOMES: NOT JUST JUNK
Dr John Hancock, Head of the Comparative Sequence Analysis Group, Medical Research Council Clinical Sciences Centre, Hammersmith Hospital

Abstract: Eukaryotic genomes are rich in repetitive sequences, some of which are not obvious to the naked eye. These sequences are habitually removed from sequences during database screening. However comparative studies, both within and between genomes, reveal associations between functional regions of genomes, and even genes of particular functional classes, and particular types of repetitive sequence. Even the orientations of repetitive sequences may provide information about the direction of replication through a genomic region. Future studies will be aimed at extending these observations and using them as tools in characterising genomic sequences.

This seminar was held at the Department of Computer Science, Royal Holloway, University of London on 23 September 1999.

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