THEORETICAL SIMULATIONS OF PROTEINS: REFINING, VALIDATING, PREDICTING STRUCTURAL DATA
Dr Franca Fraternali, National Institute for Medical Research, London

Abstract: Computational simulations are becoming an essential tool to successfully approach the post genomic era. The Structural Molecular Biology field is invaded by the enormous amount of sequences and databases and the question of which structures should be experimentally solved becomes more and more important. A few examples will be given in which computational simulations helped in the process of structure determination.

Dr. Fraternali received her PhD in Physical Chemistry at the University of Naples in 1992. She moved to the Polytechnic of Zurich to join the group of computational chemistry directed by Prof van Gunsteren. She spent two years at the University of Strasbourg in the field of computational chemistry applied to supramolecular assemblies. In 1996 she joined the group of Dr Annalisa Pastore at the European Molecular Biology Laboratories in Heidelberg, in collaboration with the group of Biocomputing. The group moved to London at MRC in 1997, and she is there with an independent research associate position.

This seminar was held at the Department of Computer Science, Royal Holloway, University of London on 22 September 1999.

back